Sergios Charntikov

ASSISTANT PROFESSOR
Phone: (603) 862-5490
Office: Psychology, McConnell Hall, Durham, NH 03824
headshot of Sergios Charntikov

Dr. Sergios (Sergey) Charntikov is an Assistant Professor of Psychology. He joined the UNH faculty in 2015 after completing his Ph.D. in behavioral neuroscience at the University of Nebraska-Lincoln. Dr. Charntikov teaches undergraduate level classes related to behavioral neuroscience and addiction. His research program focuses on applying a multidisciplinary approach to study behavior and neurobiology associated with substance use disorder. This approach encompasses a) investigation of short- and long-term effects of drugs of abuse, b) investigation and development of treatment relevant strategies, and c) improvement of existing and development of novel relapse prevention strategies. One arm of this research is focusing on understanding individual differences in substance use and in response to treatment. For example, Dr. Charntikov is interested in how individual vulnerability to stress contributes to traumatic stress and heroin use comorbidity or how individual history with nicotine or alcohol relates to various treatment outcomes. The other arm of the research in Dr. Charntikov lab focuses on the understanding of neural mechanisms underlying learning with drugs of abuse. We believe that investigating neural substrates underlying learning mechanisms with pharmacological stimuli is of great importance if the goal is to develop more effective treatment strategies. To achieve these goals, we are using a translationally relevant preclinical drug self-administration model that allows us to model relevant behavioral and neural mechanisms. We also rely on behavioral economics and advanced analytical approaches to assess individual effects and relate them to other markers of interest. Finally, our long-term goal is to able to determine the most suitable individualized treatment options for substance use disorder depending on the previous history of substance use and other behavioral or biological markers.

Education

  • Ph.D., University of Nebraska
  • M.A., Experimental Psychology, California State University
  • M.A., California State University

Research Interests

  • Behavioral neuroscience
  • Drug addiction
  • Heroin
  • Learning with drug states
  • Methamphetamine
  • Nicotine
  • Pharmacology

Courses Taught

  • INCO 590: Rsrch Exp/Neuroscience
  • INCO 790: Adv Rsrch Exp/Psychology
  • PSYC 502: Research Methods in Psychology
  • PSYC 741: Adv Top/Behaviorl Neuroscience
  • PSYC 894: Advanced Research
  • PSYC 933: Adv Sem/Physiological Psych

Selected Publications

Kazan, T., & Charntikov, S. (2019). Individual differences in responding to bupropion or varenicline in a preclinical model of nicotine self-administration vary according to individual demand for nicotine. Neuropharmacology, 148, 139-150. doi:10.1016/j.neuropharm.2018.12.031

Charntikov, S., Pittenger, S. T., Pudiak, C. M., & Bevins, R. A. (2018). The effect of N -acetylcysteine or bupropion on methamphetamine self-administration and methamphetamine–triggered reinstatement of female rats. Neuropharmacology, 135, 487-495. doi:10.1016/j.neuropharm.2018.03.021

Charntikov, S., Pittenger, S. T., Swalve, N., Li, M., & Bevins, R. A. (2017). Double dissociation of the anterior and posterior dorsomedial caudate-putamen in the acquisition and expression of associative learning with the nicotine stimulus. Neuropharmacology, 121, 111-119. doi:10.1016/j.neuropharm.2017.04.026

Charntikov, S., Falco, A. M., Fink, K., Dwoskin, L. P., & Bevins, R. A. (2017). The effect of sazetidine-A and other nicotinic ligands on nicotine controlled goal-tracking in female and male rats. Neuropharmacology, 113, 354-366. doi:10.1016/j.neuropharm.2016.10.014

Charntikov, S., Swalve, N., Pittenger, S., Fink, K., Schepers, S., Hadlock, G. C., . . . Bevins, R. A. (2016). Corrigendum to “Iptakalim attenuates self-administration and acquired goal-tracking behavior controlled by nicotine” [Neuropharmacology 75 (2013) 138–144]. Neuropharmacology, 101, 590. doi:10.1016/j.neuropharm.2015.03.025

Charntikov, S., Pittenger, S. T., Thapa, I., Bastola, D. R., Bevins, R. A., & Pendyala, G. (2015). Ibudilast reverses the decrease in the synaptic signaling protein phosphatidylethanolamine-binding protein 1 (PEBP1) produced by chronic methamphetamine intake in rats. Drug and Alcohol Dependence, 152, 15-23. doi:10.1016/j.drugalcdep.2015.04.012

Varela, F. A., Der-Ghazarian, T., Lee, R. J., Charntikov, S., Crawford, C. A., & McDougall, S. A. (2014). Repeated aripiprazole treatment causes dopamine D2 receptor up-regulation and dopamine supersensitivity in young rats. Journal of Psychopharmacology, 28(4), 376-386. doi:10.1177/0269881113504016

Iñiguez, S. D., Charntikov, S., Baella, S. A., Herbert, M. S., Bolaños-Guzmán, C. A., & Crawford, C. A. (2012). Post-training cocaine exposure facilitates spatial memory consolidation in C57BL/6 mice. Hippocampus, 22(4), 802-813. doi:10.1002/hipo.20941

Charntikov, S., Der-Ghazarian, T., Herbert, M. S., Horn, L. R., Widarma, C. B., Gutierrez, A., . . . Mcdougall, S. A. (2011). Importance of D1 and D2 receptors in the dorsal caudate-putamen for the locomotor activity and stereotyped behaviors of preweanling rats. Neuroscience, 183, 121-133. doi:10.1016/j.neuroscience.2011.03.037

McDougall, S. A., Charntikov, S., Cortez, A. M., Amodeo, D. A., Martinez, C. E., & Crawford, C. A. (2009). Persistence of one-trial cocaine-induced behavioral sensitization in young rats: regional differences in Fos immunoreactivity. Psychopharmacology, 203(3), 617-628. doi:10.1007/s00213-008-1407-1

Most Cited Publications